Over the last few weeks we have been collecting more Aspergillus fumigatus isolates from around the world to add to our ever-expanding collection. These isolates are of interest both spatially and temporally and will be used to answer some fundamental questions related to the evolution of global antifungal drug resistance.
Some of these strains have been sent to us by the good folks at Westerdijk Fungal Biodiversity Institute (check them out). We have got some fascinating specimens that will soon be heading off to Edinburgh for WGS.
In addition to these interesting isolates, we now have a number of airborne specimens collected from Hyde Park and St Mary's Hospital roof. These, along with other samples collected around London, will be genotyped for resistance in due course and potentially added to a later WGS-ing run.
Progress is moving along nicely and a neat set of clinically important isolates will soon be loaded onto the sequencer. Sequence data from our previous run is churning through our bioinformatics pipeline. And our new isolates are happily growing in our incubators.
Please continue to check back here for updates on our progress and if you have any question, please feel free to get in touch!